X-ray induced alterations in the differentiation and mineralization potential of murine preosteoblastic cells

To evaluate the effects of ionizing radiation (IR) on murine preosteoblastic cell differentiation, we directed OCT-1 cells to the osteoblastic lineage by treatment with a combination of β-glycerophosphate (β-GP), ascorbic acid (AA), and dexamethasone (Dex). In vitro mineralization was evaluated based on histochemical staining and quantification of the hydroxyapatite content of the extracellular bone matrix. Expression of mRNA encoding Runx2, transforming growth factor β1 (TGF-β1), osteocalcin (OCN), and p21^CDKN1A was analyzed. Exposure to IR reduced the growth rate and diminished cell survival of OCT-1 cells under standard conditions. Notably, calcium content analysis revealed that deposition of mineralized matrix increased significantly under osteogenic conditions after X-ray exposure in a time-dependent manner. In this study, higher radiation doses exert significant overall effects on TGF-β1, OCN, and p21^CDKN1A gene expression, suggesting that gene expression following X-ray treatment is affected in a dose-dependent manner. Additionally, we verified that Runx2 was suppressed within 24 h after irradiation at 2 and 4 Gy. Although further studies are required to verify the molecular mechanism, our observations strongly suggest that treatment with IR markedly alters the differentiation and mineralization process of preosteoblastic cells.     

The Lunar Terrestrial Observatory: Observing the Earth using photometers on the Moon’s surface

The Earth’s albedo is one of the least studied fundamental climate parameters. The albedo is a bi-directional variable, and there is a high degree of anisotropy in the light reflected from a given terrestrial surface. However, simultaneously observing from all points on Earth at all reflecting angles is a practical impossibility. Therefore, all measurements from which albedo can be inferred require assumptions and/or modeling to derive a good estimate. Nowadays, albedo measurements are taken regularly either from low Earth orbit satellite platforms or from ground-based measurements of the earthshine from the dark side of the Moon. But the results from these different measurements are not in satisfactory agreement. Clearly, the availability of different albedo databases and their inter-comparisons can help to constrain the assumptions necessary to reduce the uncertainty of the albedo estimates. In recent years, there has been a renewed interest in the development of robotic and manned exploration missions to the Moon. Returning to the Moon will enable diverse exploration and scientific opportunities. Here we discuss the possibility of a lunar-based Earth radiation budget monitoring experiment, the Lunar Terrestrial Observatory, and evaluate its scientific and practical advantages compared to the other, more standard, observing platforms. We conclude that a lunar-based terrestrial observatory can enable advances in Earth sciences, complementary to the present efforts, and to our understanding of the Earth’s climate.     

Dynamical evolution of high area-to-mass ratio debris released into GPS orbits

A large set of simulations, including all the relevant perturbations, was carried out to investigate the long-term dynamical evolution of fictitious high area-to-mass ratio (A/M) objects released, with a negligible velocity variation, in each of the six orbital planes used by Global Positioning System (GPS) satellites. As with similar objects discovered in near synchronous trajectories, long lifetime orbits, with mean motions of about 2 revolutions per day, were found possible for debris characterized by extremely high area-to-mass ratios. Often the lifetime exceeds 100 years up to A/M ∼ 45 m²/kg, decreasing rapidly to a few months above such a threshold. However, the details of the evolution, which are conditioned by the complex interplay of solar radiation pressure and geopotential plus luni-solar resonances, depend on the initial conditions. Different behaviors are thus possible. In any case, objects like those discovered in synchronous orbits, with A/M as high as 20–40 m²/kg, could also survive in this orbital regime, with semi-major axes close to the semi-synchronous values, with maximum eccentricities between 0.3 and 0.7, and with significant orbit pole precessions (faster and wider for increasing values of A/M), leading to inclinations between 30° and more than 90°.     

加热切削GH135吸收会焦辐射能的研究

本文介绍了采用高效金属素灯作为加热热源切削ＧＨ１３５等难加工材料的方法。采用该方法可有效改善难加工材料的切削性能，本文重点介绍了辐射能量传递的分析及有效的能量公式。同时指出该方法投产少，使用简单，便于推广等特点，因此具有很好的应用前景。     

Thermal cyclotron radiation from a hot coronal loop with helical magnetic field

The spectral and polarization properties of thermal cyclotron radio emission from a hot coronal loop with a current along the axis are computed. The magnetic field is supposed to have a component along the loop axis as well as a poloidal part due to the current, both components being of comparable magnitude. In this specific configuration a helical magnetic field is present with a remarkable minimum of its absolute value along the loop axis and a maximum at its periphery. The presence of one or two maxima of magnetic field value along the line of sight results in increasing optical thickness of the gyroresonance layers at appropriate frequencies in the microwave band and, therefore, in enhanced radio emission at those harmonics which are optically thin (for example,s=4). These cannot be observed in models with the commonly employed magnetic field configuration (longitudinal along the loop axis).We show that the frequency spectrum of thermal cyclotron radiation from a hot coronal loop with a helical magnetic field differs from that of the standards-component source (with smooth frequency characteristics and polarization corresponding toe-mode) in that plenty of fine structures (line-like features and cut-offs) are present and theo-mode is prevalent in some frequency intervals. The enhanced radio emission at high harmonics and the complicated form of frequency spectrum in the model considered imply that some microwave sources, which are poorly explained in traditional models of solar active regions, may be associated with helical magnetic fields in hot coronal loops. Computations allow one to indicate spectral and polarizational peculiarities of local sources testifying to the presence of a helical magnetic field.     

基于SRAM型FPGA单粒子效应综合防护技术

为解决基于SRAM(Static Random Access Memory,静态随机存储器)型FPGA(Field Programmable Gate Array,现场可编程门阵列)的扩频应答机在空间环境中时常发生功能故障的难题,提出了一种低轨卫星基于SRAM型FPGA的应答机的单粒子综合防护方案。该方案在代码级、器件级、单机级、整星级综合采用器件优选、结构屏蔽设计、巡检自愈、自主复位等多种方法,有效杜绝了单粒子事件带来的种种危害,已成功应用于某在轨卫星。在轨测试结果表明:遥测、遥控、跟踪测量等功能、性能指标满足任务要求,且未发生需要地面干预的问题或现象。该技术还可推广应用于其他采用低等级器件及其他类型FPGA、DSP(Digital Signal Processing,数字信号处理)等大规模集成电路的星载单机防护。     

温度传感器辐射修正校准的准确牲研究

为了确定温度传感器辐射修正校准的准确性，需要对温度传感器辐射修正校准结果进行对比及不确定度分析。本文介绍了在热校准风洞中进行温度传感器辐射修正校准的结果，并做了对比研究和不确定度分析。     

On a non-primordial origin of the cosmic background radiation and pregalactic density fluctuations

Dusty pregalactic Population III objects may provide a mechanism for an effective thermalization of the star radiation. They may generate the observed microwave background and so the high cosmic photon entropy. Assuming a tepid universe a smaller primordial entropy contribution results in reasonable mass scales and amplification factors of pregalactic density fluctuations.     

Hi content in cluster and supercluster galaxies

In this lecture I review part of the published and unpublished observational evidence showing that cluster spiral galaxies are hydrogen deficient. Always using observational data, it is argued that the deficiency is due to the interaction between the galaxies and the intergalactic medium. Furthermore it is shown that the stellar population of deficient galaxies has also been affected and a brief discussion is given of the mechanisms at work.     

First results from the LUCID-Timepix spacecraft payload onboard the TechDemoSat-1 satellite in Low Earth Orbit

The Langton Ultimate Cosmic ray Intensity Detector (LUCID) is a payload onboard the satellite TechDemoSat-1, used to study the radiation environment in Low Earth Orbit ($～$635?km). LUCID operated from 2014 to 2017, collecting over 2.1 million frames of radiation data from its five Timepix detectors on board. LUCID is one of the first uses of the Timepix detector technology in open space, with the data providing useful insight into the performance of this technology in new environments. It provides high-sensitivity imaging measurements of the mixed radiation field, with a wide dynamic range in terms of spectral response, particle type and direction. The data has been analysed using computing resources provided by GridPP, with a new machine learning algorithm that uses the Tensorflow framework. This algorithm provides a new approach to processing Medipix data, using a training set of human labelled tracks, providing greater particle classification accuracy than other algorithms. For managing the LUCID data, we have developed an online platform called Timepix Analysis Platform at School (TAPAS). This provides a swift and simple way for users to analyse data that they collect using Timepix detectors from both LUCID and other experiments. We also present some possible future uses of the LUCID data and Medipix detectors in space.